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Telomerase

Telomerase functions as part of a large ensemble of proteins and RNA called the telomerase ribonucleoprotein complex

  • The end of chromosomes undergo remorseless shortening
  • The telomerase complex repairs these ends, or telomeres allowing cells to grow endlessly
  • Telomerase, or more technicallytelomerase reverse transcriptase or TERT, in the key component of this complex.

TERT inhibition induces cancer cell death

TERT inhibition induces cancer cells death